Which of the following would NOT typically be handled by a System Administrator?

The task of designing application interfaces typically falls under the responsibilities of application developers or business analysts rather than system administrators. While system administrators play a crucial role in maintaining the overall health of the system, managing infrastructure, and ensuring security, the design of user interfaces requires a deep understanding of user experience and application logic that is usually outside of the system administrator's purview.

In contrast, setting application parameters, configuring workflow settings, and managing user accounts are all essential duties of a system administrator. These tasks involve overseeing the application's operational aspects and ensuring that settings align with the organizational requirements and that users have appropriate access rights. Thus, they require a more technical expertise specific to the system's operation rather than the design focus.